Sucralose found in common sweetener damages DNA

@Jimmy Joy: Is there a possibility to replace that sweetener with something else? I don’t know which replacement is the best because they all have major drawbacks.

The reason I’m posting this is because I’m a big Jimmy Joy eater. I eat about 13 bags a month so that’s quite a bit of sucralose I’m getting. If I was consuming about 4 bags a month then I wouldn’t worry because the amount of sucralose I get is negligible because you guys use very little sucralose per meal.

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hey hey, thanks for sharing. I saw this study too and I immediately asked our team what they think of it . This is what our R&D team had to say:

"While this study suggests that sucralose may damage DNA and enteric tissue, it’s important to note that this study does not provide absolute proof and only shows a potential correlation. There is currently no conclusive evidence to support the claim that sucralose causes cancer in humans even though the study shows the byproduct sucralose-6-acetate as clastogenic (breaks DNA). For perspective, UV light is also clastogenic, just like the research suggests sucralose-6-acetate might be. It’s crucial to understand the limitations of this study, as it primarily focused on in vitro findings, which alone are not enough to establish genotoxicity.

Various guidelines, including those from the FDA, recommend testing compounds in bacteria or in vitro first. If positive results are obtained, further in vivo testing is required before any conclusions can be drawn.
The potential adverse health effects specifically related to sucralose-6-acetate traces have not been individually tested using a comprehensive battery of toxicology tests to assess human risks.

It’s worth noting that sucralose is not listed as a carcinogen (nor sucralose-6-acetate) by organizations such as the International Agency for Research on Cancer (IARC). According to their classification, if a substance is not in Group 1, Group 2A, or Group 2B, it means there isn’t sufficient evidence to classify it as a potential carcinogen.

It’s important to approach these findings with caution and continue conducting further studies. Genes associated with inflammation, oxidative stress, and cancer were found to be affected, but more research is needed to understand the specific mechanisms and potential health risks associated with sucralose consumption.

In conclusion, while the study raises concerns, it does not provide conclusive evidence of sucralose intake carcinogenic effects. Ongoing research and adherence to comprehensive testing protocols are necessary to establish a clearer understanding of the potential risks and impact of sucralose on human health.

While sucralose has been deemed safe for decades, we recognize that customer preferences can change, and we want to provide options that align with new preferences and concerns. We continue to explore alternative sweeteners."

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Thanks for the very detailed response.

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I expect JimmyJoy R&D to take this very seriously, and to take precautions when necessary.

Statements the researches made like " Our new work establishes that sucralose-6-acetate is genotoxic, (…) We also found that trace amounts of sucralose-6-acetate can be found in off-the-shelf sucralose, even before it is consumed and metabolized. (…) To put this in context, the European Food Safety Authority has a threshold of toxicological concern for all genotoxic substances of 0.15 micrograms per person per day, (…) Our work suggests that the trace amounts of sucralose-6-acetate in a single, daily sucralose-sweetened drink exceed that threshold. And that’s not even accounting for the amount of sucralose-6-acetate produced as metabolites after people consume sucralose." still worry me.

Does the sucralose-free version of Plennyshake still exist?

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This revelation is worrying enough that I won’t be purchasing any more Jimmy Joy products as long as they contain sucralose. The use of sucralose in Jimmy Joy products has worried me from the start (as did the presence of fluoride), but I was willing to overlook it since there wasn’t any evidence that sucralose is dangerous. Now there is.

I don’t understand why Jimmy Joy uses sucralose in the first place. I assume it’s to avoid distorting the macronutrient profile, but does Plenny Shake even need to be sweetened? I find most beverages too sweet, and Plenny Shake is no exception.

Can we please just have an unsweetened, unflavored Plenny Shake? I always prepare Plenny Shake in my blender with a banana for texture anyway, so throwing in my own fresh berries would not be a major hurdle.

Sucralose is in many different products that can be found in the supermarket. Jimmy Joy’s competition also uses sucralose. Some competitors of Jimmy Joy use stevia instead of sucralose, but stevia also has disadvantages

We want to assure you that we take this matter very seriously. We have
reviewed the study and its methodology (again, experiments using way higher concentrations than regular human intake). Additionally, we reached out to the author to obtain access to the report containing the evaluation of the concentration of S6A, which is mentioned to be 0.67%. Unfortunately, this report is not accessible as it was a requested analysis without a formal publication. This kind of data must be assessed several times before confirming it. Nevertheless, we are in the process of expressing our position on this study and similar ones in general.

When making strong statements, such as those regarding carcinogenic properties, it is crucial to undergo careful evaluation, repetition, and a detailed experimental process. A robust conclusion regarding correlation requires meta-analysis and systematic reviews, which minimize the likelihood of biased correlations. For instance, the correlation should be something like “people that consume sucralose have a higher rate of cancer”, but that has not been the case. There is absolutely no strong evidence showing any correlation between sucralose and cancer. For a particular molecule and its toxicological properties the research follows other steps, which haven’t been followed until now.

We utilize sucralose in our products because it has undergone extensive testing and has been approved as safe by global food safety and regulatory bodies, including the EFSA and FDA. The rigorous testing program conducted on sucralose is one of the most comprehensive, establishing a consensus on its safety among the scientific and regulatory community.

While science encourages experimentation and the acquisition of new knowledge, it is unfair for the media to present this study as conclusive data, causing confusion and fear among consumers. This study raises some concerns that warrant further investigation, but it is premature to draw any conclusions based solely on this paper.

It’s really important to be cautious when comparing information shared by the regular media with the original research publications. For instance, in the article from MedicalNewsToday that was shared, they claim that the chemical is found in Splenda. However, it’s worth noting that the research paper itself never mentions the name “Splenda” and fails to clarify the specific samples that were analyzed. Splenda has already responded to these publications, stating that they conduct thorough purity analysis and ensure that their product does not contain S6A. The main point here is not to defend Splenda, but rather to emphasize that drawing conclusions solely from one research publication is not advisable. It’s essential to consider a broader range of studies and evidence before jumping to definitive conclusions.

Right now, the EFSA is taking a fresh look at the list of allowed food additives, including sweeteners like sucralose. They want to reevaluate these ingredients in a systematic way and provide scientific opinions based on the latest research. To make sure they have all the relevant information, they made an open invitation to interested parties and stakeholders to share any documented data they have on sucralose. This way, everyone gets a chance to contribute their insights and perspectives to the evaluation process. It’s an inclusive approach that aims to make well-informed decisions about the safety of sucralose. We are on top of it to have the latest scientific opinions and guidelines to guarantee the safety of our meals.

As we mentioned before, we’re aware that our customers’ tastes and preferences can change over time, and we want to keep up with that. While sucralose has been considered safe for a long time, we’re currently looking into other alternatives to make sure our meals remain healthy, affordable, and tasty. It’s important for us to continuously improve and cater to the evolving needs and desires of our customers.

@mwhitlock unfortunately, we do not offer the neutral Plenny Shake Active anymore.

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It’s always worth being a bit sceptical whenever you see the words “may cause”. It means they don’t know for certain.

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Right, I understand it’s not a certainty. I just don’t understand why Jimmy Joy uses sucralose at all. Why even take a chance? Would plain old sucrose really screw up their formula that much?

On the other hand, one of the primary reasons I switched to Jimmy Joy over its competitors is that it doesn’t give me sugar highs and subsequent crashes, whereas the others do. Maybe I would have that problem with it if they used sucrose instead of sucralose. Of course, my preference is just to eliminate the sweetener altogether, as I see it as a needless additive. However, I do understand that Jimmy Joy has to meet the expectations of a population that is addicted to sweet drinks and that their sales would suffer if they didn’t sweeten Plenny Shake. Most unfortunate.

Sucrose is far less sweet, so much more of it would be needed. I’m certainly no expert, but it seems that there are more solid links between high sugar consumption and various health problems.

However, I do think it is a shame that Jimmy Joy no longer does the unsweetened version. But JJ only keep producing products that are popular, so obviously not enough people were buying that. It does seem strange to me, though, as there are many flavourings you can buy, which take a few seconds to put into the bottle. If anything, it would make more sense for JJ to just make an unsweetened version but then sell a variety of flavourings for people to add.

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To be fair, Jimmy Joy flavor their shakes with real ingredients, which carry real nutrients, so they might need to adjust other components to maintain exact nutrient ratios. They couldn’t do that if they sold mix-in flavorings separately.

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Hello, I am a recent new customer of Jimmy Joy. While I love the products I have recently become aware of the side effects and potential harm assoiated with one of the ingredients used in these products, sucralose. Not only does sucralose cause headaches, but it can lead to other side effects, including:

Gastrointestinal distress like bloating, gas, cramps, and diarrhea

An altered gut microbiome, potentially affecting overall gut health

Increased sweet cravings

A negative impact on your metabolism, including weight gain and insulin resistance

I am on a mission in terms of sugar, there are other options; monk fruit sweeter is really good, date sugar has a low glygemic ndex, both derived from plants.

hey @YvonneK, welcome to our forum! :tada:

Thank you for sharing your thoughts and giving our product a try! We truly value feedback from our customers. Allow us to address your concerns regarding sucralose:

Sucralose has been widely used as a sweetener for decades and has undergone extensive safety testing by regulatory bodies around the world. Both the European Food Safety Authority (EFSA) and the U.S. Food and Drug Administration (FDA) have reviewed sucralose and approved it as safe for consumption, even at levels far beyond what people typically consume daily. The EFSA is currently re-evaluating all approved food additives, including sucralose, to ensure their continued safety based on the latest research. We closely monitor these updates and will always prioritize safety and transparency in our products.

Regarding the specific concerns you’ve mentioned:

  1. Headaches: While anecdotal reports of headaches exist, large-scale scientific studies have not established a causal link between sucralose consumption and headaches. However, individual sensitivities can vary, and if you suspect a reaction, it’s always good to consult a healthcare professional.
  2. Gastrointestinal distress: Some studies suggest that very high doses of sucralose (far exceeding what is found in food products) may alter gut bacteria in animals. However, current research does not demonstrate significant negative effects on gut health in humans at the levels approved for use in food.
  3. Sweet cravings and metabolism: Research has not consistently shown that sucralose consumption increases cravings or negatively impacts metabolism when consumed within approved limits and as part of a balanced diet. Many studies confirm that sucralose does not affect blood sugar levels or insulin response in the general population, making it a suitable option for people managing blood sugar levels.
  4. Weight gain and insulin resistance: Sucralose has zero calories and is often used as an alternative to sugar to help reduce overall calorie intake. There is no conclusive evidence that sucralose contributes to weight gain or insulin resistance when consumed as part of a balanced diet.

There have been observations that when people trying to lose weight consume products containing sucralose while avoiding carbohydrates, they may experience sweet cravings. This happens because carbohydrates are the body’s primary fuel source, and avoiding them can trigger the body to seek alternative energy sources, leading to cravings. As a result, some people may end up overeating other foods or consuming simple carbs later on, potentially contributing to weight gain.

This highlights the importance of understanding the interplay between sucralose, dietary choices, and their effects on the body. However, it’s important to note that sucralose itself is not necessarily the direct cause of issues like weight gain, insulin resistance, or sweet cravings—it’s more about how these factors interact with one another in the context of overall diet and lifestyle.

We understand your interest in natural sweeteners like monk fruit and date sugar, and we are actively exploring alternative sweeteners to cater to different preferences. However, each sweetener has its own set of challenges, including availability, taste, cost, and impact on the nutritional profile of our products. Our goal is to ensure that our meals remain nutritious, affordable, and enjoyable while accommodating a range of dietary preferences. For example, monk fruit sweetener is not yet approved in the European Union so we cannot add it to our products. Date sugar doesn’t dissolve well in drinks, since it is ground dates and it will increase the sugar content, which we aim to keep low.

Your mission to reduce sugar and focus on plant-derived alternatives aligns with our commitment to offering sustainable and health-conscious meals. While sucralose remains a well-tested and safe ingredient, we appreciate your feedback and will continue to explore ways to innovate and meet the evolving needs of our customers :green_heart:

If you still prefer meals without sucralose, our Plenny Bar Almond&Fig doesn’t have sucralose. Additionally, we have the Plenny Protein shake Neutral (not a meal, but a protein shake) which has no flavour or sweetener.

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